PDB 4i9n

PDB Links
Overview

PDB Information

PDB	4I9N
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors. Kohlmann, A., Zech, S.G., Li, F., Zhou, T., Squillace, R.M., Commodore, L., Greenfield, M.T., Lu, X., Miller, D.P., Huang, W.S., Qi, J., Thomas, R.M., Wang, Y., Zhang, S., Dodd, R., Liu, S., Xu, R., Xu, Y., Miret, J.J., Rivera, V., Clackson, T., Shakespeare, W.C., Zhu, X., Dalgarno, D.C. J.Med.Chem.
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2012-12-05
Resolution	2.350
CATH Insert Date	27 Jan, 2013

PDB Images (25)

4i9n

PDB 4i9n

4i9nA

PDB Chain 4i9nA

4i9nB

PDB Chain 4i9nB

4i9nC

PDB Chain 4i9nC

4i9nD

PDB Chain 4i9nD

4i9nE

PDB Chain 4i9nE

4i9nF

PDB Chain 4i9nF

4i9nG

PDB Chain 4i9nG

4i9nH

PDB Chain 4i9nH

4i9nA01

CATH Domain 4i9nA01

4i9nA02

CATH Domain 4i9nA02

4i9nB01

CATH Domain 4i9nB01

4i9nB02

CATH Domain 4i9nB02

4i9nC01

CATH Domain 4i9nC01

4i9nC02

CATH Domain 4i9nC02

4i9nD01

CATH Domain 4i9nD01

4i9nD02

CATH Domain 4i9nD02

4i9nE01

CATH Domain 4i9nE01

4i9nE02

CATH Domain 4i9nE02

4i9nF01

CATH Domain 4i9nF01

4i9nF02

CATH Domain 4i9nF02

4i9nG01

CATH Domain 4i9nG01

4i9nG02

CATH Domain 4i9nG02

4i9nH01

CATH Domain 4i9nH01

4i9nH02

CATH Domain 4i9nH02

PDB Prints

PDB Chains (8)

Chain ID	Date inserted into CATH	CATH Status
A	28 Jan, 2013	Chopped
B	28 Jan, 2013	Chopped
C	28 Jan, 2013	Chopped
D	28 Jan, 2013	Chopped
E	28 Jan, 2013	Chopped
F	28 Jan, 2013	Chopped
G	28 Jan, 2013	Chopped
H	28 Jan, 2013	Chopped

CATH Domains (16)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4i9nA01	02 Feb, 2013	3.40.50.720	Assigned
4i9nA02	02 Feb, 2013	3.90.110.10	Assigned
4i9nB01	02 Feb, 2013	3.40.50.720	Assigned
4i9nB02	02 Feb, 2013	3.90.110.10	Assigned
4i9nC01	02 Feb, 2013	3.40.50.720	Assigned
4i9nC02	02 Feb, 2013	3.90.110.10	Assigned
4i9nD01	02 Feb, 2013	3.40.50.720	Assigned
4i9nD02	02 Feb, 2013	3.90.110.10	Assigned
4i9nE01	02 Feb, 2013	3.40.50.720	Assigned
4i9nE02	02 Feb, 2013	3.90.110.10	Assigned
4i9nF01	02 Feb, 2013	3.40.50.720	Assigned
4i9nF02	02 Feb, 2013	3.90.110.10	Assigned
4i9nG01	02 Feb, 2013	3.40.50.720	Assigned
4i9nG02	02 Feb, 2013	3.90.110.10	Assigned
4i9nH01	02 Feb, 2013	3.40.50.720	Assigned
4i9nH02	02 Feb, 2013	3.90.110.10	Assigned

UniProtKB Entries (8)

Accession	Gene ID	Taxon	Description
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain
P13491	LDHA_RABIT	Oryctolagus cuniculus	L-lactate dehydrogenase A chain