PDB 4i5c

PDB Links
Overview

PDB Information

PDB	4I5C
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Novel triazolo-pyrrolopyridines as inhibitors of Janus kinase 1. Hurley, C.A., Blair, W.S., Bull, R.J., Chang, C., Crackett, P.H., Deshmukh, G., Dyke, H.J., Fong, R., Ghilardi, N., Gibbons, P., Hewitt, P.R., Johnson, A., Johnson, T., Kenny, J.R., Kohli, P.B., Kulagowski, J.J., Liimatta, M., Lupardus, P.J., Maxey, R.J., Mendonca, R., Narukulla, R., Pulk, R., Ubhayakar, S., van Abbema, A., Ward, S.I., Waszkowycz, B., Zak, M. Bioorg.Med.Chem.Lett.
Header	Transferase
Released	2012-11-28
Resolution	2.100
CATH Insert Date	07 Jul, 2013

PDB Images (7)

Image of CATH 4i5c

4i5c

PDB 4i5c

Image of CATH 4i5cA

4i5cA

PDB Chain 4i5cA

Image of CATH 4i5cB

4i5cB

PDB Chain 4i5cB

Image of CATH 4i5cA01

4i5cA01

CATH Domain 4i5cA01

Image of CATH 4i5cA02

4i5cA02

CATH Domain 4i5cA02

Image of CATH 4i5cB01

4i5cB01

CATH Domain 4i5cB01

Image of CATH 4i5cB02

4i5cB02

CATH Domain 4i5cB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	08 Jul, 2013	Chopped
B	08 Jul, 2013	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4i5cA01	09 Aug, 2013	3.30.200.20	Assigned
4i5cA02	09 Aug, 2013	1.10.510.10	Assigned
4i5cB01	09 Aug, 2013	3.30.200.20	Assigned
4i5cB02	09 Aug, 2013	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P23458	JAK1_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK1
P23458	JAK1_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK1