PDB 4hx3
PDB Information
| PDB | 4HX3 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Streptomyces caespitosus |
| Primary Citation | Mechanism of action of a Janus-faced single-domain protein inhibitor simultaneously targeting two peptidase classes
CHEM SCI
|
| Header | Hydrolase/Hydrolase Inhibitor |
| Released | 2012-11-09 |
| Resolution | 2.700 |
| CATH Insert Date | 30 Dec, 2012 |
PDB Images (25)
4hx3
PDB 4hx3
4hx3A
PDB Chain 4hx3A
4hx3B
PDB Chain 4hx3B
4hx3C
PDB Chain 4hx3C
4hx3D
PDB Chain 4hx3D
4hx3E
PDB Chain 4hx3E
4hx3F
PDB Chain 4hx3F
4hx3G
PDB Chain 4hx3G
4hx3H
PDB Chain 4hx3H
4hx3I
PDB Chain 4hx3I
4hx3J
PDB Chain 4hx3J
4hx3K
PDB Chain 4hx3K
4hx3L
PDB Chain 4hx3L
4hx3A00
CATH Domain 4hx3A00
4hx3B00
CATH Domain 4hx3B00
4hx3C00
CATH Domain 4hx3C00
4hx3D00
CATH Domain 4hx3D00
4hx3E00
CATH Domain 4hx3E00
4hx3F00
CATH Domain 4hx3F00
4hx3G00
CATH Domain 4hx3G00
4hx3H00
CATH Domain 4hx3H00
4hx3I00
CATH Domain 4hx3I00
4hx3J00
CATH Domain 4hx3J00
4hx3K00
CATH Domain 4hx3K00
4hx3L00
CATH Domain 4hx3L00
PDB Prints
PDB Chains (12)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 31 Dec, 2012 | Chopped |
| B | 31 Dec, 2012 | Chopped |
| C | 31 Dec, 2012 | Chopped |
| D | 31 Dec, 2012 | Chopped |
| E | 31 Dec, 2012 | Chopped |
| F | 31 Dec, 2012 | Chopped |
| G | 31 Dec, 2012 | Chopped |
| H | 31 Dec, 2012 | Chopped |
| I | 31 Dec, 2012 | Chopped |
| J | 31 Dec, 2012 | Chopped |
| K | 31 Dec, 2012 | Chopped |
| L | 31 Dec, 2012 | Chopped |
CATH Domains (12)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4hx3A00 | 02 Jan, 2013 | 3.40.390.10 | Assigned |
| 4hx3B00 | 03 Jan, 2013 | 3.30.350.10 | Assigned |
| 4hx3C00 | 03 Jan, 2013 | 3.40.390.10 | Assigned |
| 4hx3D00 | 03 Jan, 2013 | 3.30.350.10 | Assigned |
| 4hx3E00 | 03 Jan, 2013 | 3.40.390.10 | Assigned |
| 4hx3F00 | 03 Jan, 2013 | 3.30.350.10 | Assigned |
| 4hx3G00 | 03 Jan, 2013 | 3.40.390.10 | Assigned |
| 4hx3H00 | 03 Jan, 2013 | 3.30.350.10 | Assigned |
| 4hx3I00 | 02 Jan, 2013 | 3.40.390.10 | Assigned |
| 4hx3J00 | 02 Jan, 2013 | 3.30.350.10 | Assigned |
| 4hx3K00 | 03 Jan, 2013 | 3.40.390.10 | Assigned |
| 4hx3L00 | 03 Jan, 2013 | 3.30.350.10 | Assigned |
UniProtKB Entries (12)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P56406 | SNPA_STRCS | Streptomyces caespitosus | Extracellular small neutral protease |
| P56406 | SNPA_STRCS | Streptomyces caespitosus | Extracellular small neutral protease |
| Q9FDS0 | Q9FDS0_STRCS | Streptomyces caespitosus | Neutral proteinase inhibitor ScNPI |
| Q9FDS0 | Q9FDS0_STRCS | Streptomyces caespitosus | Neutral proteinase inhibitor ScNPI |
| Q9FDS0 | Q9FDS0_STRCS | Streptomyces caespitosus | Neutral proteinase inhibitor ScNPI |
| Q9FDS0 | Q9FDS0_STRCS | Streptomyces caespitosus | Neutral proteinase inhibitor ScNPI |
| P56406 | SNPA_STRCS | Streptomyces caespitosus | Extracellular small neutral protease |
| Q9FDS0 | Q9FDS0_STRCS | Streptomyces caespitosus | Neutral proteinase inhibitor ScNPI |
| P56406 | SNPA_STRCS | Streptomyces caespitosus | Extracellular small neutral protease |
| P56406 | SNPA_STRCS | Streptomyces caespitosus | Extracellular small neutral protease |
| P56406 | SNPA_STRCS | Streptomyces caespitosus | Extracellular small neutral protease |
| Q9FDS0 | Q9FDS0_STRCS | Streptomyces caespitosus | Neutral proteinase inhibitor ScNPI |
