PDB 4hww

PDB Information

PDB4HWW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of (R)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury.
Van Zandt, M.C., Whitehouse, D.L., Golebiowski, A., Ji, M.K., Zhang, M., Beckett, R.P., Jagdmann, G.E., Ryder, T.R., Sheeler, R., Andreoli, M., Conway, B., Mahboubi, K., D'Angelo, G., Mitschler, A., Cousido-Siah, A., Ruiz, F.X., Howard, E.I., Podjarny, A.D., Schroeter, H.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-11-09
Resolution1.300
CATH Insert Date28 Mar, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped
B 28 Mar, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4hwwA00 10 Apr, 2013 3.40.800.10 Assigned
4hwwB00 10 Apr, 2013 3.40.800.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P05089 ARGI1_HUMAN Homo sapiens Arginase-1
P05089 ARGI1_HUMAN Homo sapiens Arginase-1