PDB Information

PDB4HWO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEscherichia coli
Primary Citation
Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design.
Teng, M., Hilgers, M.T., Cunningham, M.L., Borchardt, A., Locke, J.B., Abraham, S., Haley, G., Kwan, B.P., Hall, C., Hough, G.W., Shaw, K.J., Finn, J.
J.Med.Chem.
HeaderLigase/Ligase Inhibitor
Released2012-11-08
Resolution1.910
CATH Insert Date22 Sep, 2013

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 23 Sep, 2013 Chopped
B 23 Sep, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4hwoA01 03 Oct, 2013 3.30.930.10 Assigned
4hwoA02 03 Oct, 2013 3.40.50.800 Assigned
4hwoB01 03 Oct, 2013 3.30.930.10 Assigned
4hwoB02 03 Oct, 2013 3.40.50.800 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P0A8M3 SYT_ECOLI Escherichia coli K-12 Threonine--tRNA ligase
P0A8M3 SYT_ECOLI Escherichia coli K-12 Threonine--tRNA ligase