PDB 4htx
PDB Information
| PDB | 4HTX |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | X-ray Crystal Structure of Phosphodiesterase 2 in Complex with a Highly Selective, Nanomolar Inhibitor Reveals a Binding-Induced Pocket Important for Selectivity.
J.Am.Chem.Soc.
|
| Header | Hydrolase/Hydrolase Inhibitor |
| Released | 2012-11-02 |
| Resolution | 1.900 |
| CATH Insert Date | 15 Sep, 2013 |
PDB Prints
PDB Chains (4)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 16 Sep, 2013 | Chopped |
| B | 16 Sep, 2013 | Chopped |
| C | 16 Sep, 2013 | Chopped |
| D | 16 Sep, 2013 | Chopped |
CATH Domains (4)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4htxA00 | 18 Sep, 2013 | 1.10.1300.10 | Assigned |
| 4htxB00 | 18 Sep, 2013 | 1.10.1300.10 | Assigned |
| 4htxC01 | 18 Sep, 2013 | 1.10.1300.10 | Assigned |
| 4htxD01 | 18 Sep, 2013 | 1.10.1300.10 | Assigned |
UniProtKB Entries (4)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| O00408 | PDE2A_HUMAN | Homo sapiens | cGMP-dependent 3',5'-cyclic phosphodiesterase |
| O00408 | PDE2A_HUMAN | Homo sapiens | cGMP-dependent 3',5'-cyclic phosphodiesterase |
| O00408 | PDE2A_HUMAN | Homo sapiens | cGMP-dependent 3',5'-cyclic phosphodiesterase |
| O00408 | PDE2A_HUMAN | Homo sapiens | cGMP-dependent 3',5'-cyclic phosphodiesterase |
