PDB 4htx

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PDB Links
Overview

PDB Information

PDB	4HTX
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	X-ray Crystal Structure of Phosphodiesterase 2 in Complex with a Highly Selective, Nanomolar Inhibitor Reveals a Binding-Induced Pocket Important for Selectivity. Zhu, J., Yang, Q., Dai, D., Huang, Q. J.Am.Chem.Soc.
Header	Hydrolase/Hydrolase Inhibitor
Released	2012-11-02
Resolution	1.900
CATH Insert Date	15 Sep, 2013

PDB Images (9)

Image of CATH 4htx

4htx

PDB 4htx

Image of CATH 4htxA

4htxA

PDB Chain 4htxA

Image of CATH 4htxB

4htxB

PDB Chain 4htxB

Image of CATH 4htxC

4htxC

PDB Chain 4htxC

Image of CATH 4htxD

4htxD

PDB Chain 4htxD

Image of CATH 4htxA00

4htxA00

CATH Domain 4htxA00

Image of CATH 4htxB00

4htxB00

CATH Domain 4htxB00

Image of CATH 4htxC01

4htxC01

CATH Domain 4htxC01

Image of CATH 4htxD01

4htxD01

CATH Domain 4htxD01

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	16 Sep, 2013	Chopped
B	16 Sep, 2013	Chopped
C	16 Sep, 2013	Chopped
D	16 Sep, 2013	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4htxA00	18 Sep, 2013	1.10.1300.10	Assigned
4htxB00	18 Sep, 2013	1.10.1300.10	Assigned
4htxC01	18 Sep, 2013	1.10.1300.10	Assigned
4htxD01	18 Sep, 2013	1.10.1300.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase