PDB 4htx

PDB Information

PDB4HTX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
X-ray Crystal Structure of Phosphodiesterase 2 in Complex with a Highly Selective, Nanomolar Inhibitor Reveals a Binding-Induced Pocket Important for Selectivity.
Zhu, J., Yang, Q., Dai, D., Huang, Q.
J.Am.Chem.Soc.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-11-02
Resolution1.900
CATH Insert Date15 Sep, 2013

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Sep, 2013 Chopped
B 16 Sep, 2013 Chopped
C 16 Sep, 2013 Chopped
D 16 Sep, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4htxA00 18 Sep, 2013 1.10.1300.10 Assigned
4htxB00 18 Sep, 2013 1.10.1300.10 Assigned
4htxC01 18 Sep, 2013 1.10.1300.10 Assigned
4htxD01 18 Sep, 2013 1.10.1300.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O00408 PDE2A_HUMAN Homo sapiens cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408 PDE2A_HUMAN Homo sapiens cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408 PDE2A_HUMAN Homo sapiens cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408 PDE2A_HUMAN Homo sapiens cGMP-dependent 3',5'-cyclic phosphodiesterase