PDB 4hdc

PDB Information

PDB4HDC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStaphylococcus aureus subsp. aureus
Primary Citation
Discovery of Selective and Potent Inhibitors of Gram-Positive Bacterial Thymidylate Kinase (TMK).
Martinez-Botella, G., Breen, J.N., Duffy, J.E., Dumas, J., Geng, B., Gowers, I.K., Green, O.M., Guler, S., Hentemann, M.F., Hernandez-Juan, F.A., Joseph-McCarthy, D., Kawatkar, S., Larsen, N.A., Lazari, O., Loch, J.T., Macritchie, J.A., McKenzie, A.R., Newman, J.V., Olivier, N.B., Otterson, L.G., Owens, A.P., Read, J., Sheppard, D.W., Keating, T.A.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-10-02
Resolution2.050
CATH Insert Date04 Nov, 2012

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4hdcA00 11 Nov, 2012 3.40.50.300 Assigned
4hdcB00 11 Nov, 2012 3.40.50.300 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P65249 KTHY_STAAN Staphylococcus aureus subsp. aureus N315 Thymidylate kinase
P65249 KTHY_STAAN Staphylococcus aureus subsp. aureus N315 Thymidylate kinase
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