PDB 4h58

PDB Links
Overview

PDB Information

PDB	4H58
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery and Optimization of a Novel Series of Potent Mutant B-Raf(V600E) Selective Kinase Inhibitors. Vasbinder, M.M., Aquila, B., Augustin, M., Chen, H., Cheung, T., Cook, D., Drew, L., Fauber, B.P., Glossop, S., Grondine, M., Hennessy, E., Johannes, J., Lee, S., Lyne, P., Mortl, M., Omer, C., Palakurthi, S., Pontz, T., Read, J., Sha, L., Shen, M., Steinbacher, S., Wang, H., Wu, A., Ye, M. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2012-09-18
Resolution	3.100
CATH Insert Date	28 Mar, 2013

PDB Images (10)

Image of CATH 4h58

4h58

PDB 4h58

Image of CATH 4h58A

4h58A

PDB Chain 4h58A

Image of CATH 4h58B

4h58B

PDB Chain 4h58B

Image of CATH 4h58C

4h58C

PDB Chain 4h58C

Image of CATH 4h58A01

4h58A01

CATH Domain 4h58A01

Image of CATH 4h58A02

4h58A02

CATH Domain 4h58A02

Image of CATH 4h58B01

4h58B01

CATH Domain 4h58B01

Image of CATH 4h58B02

4h58B02

CATH Domain 4h58B02

Image of CATH 4h58C01

4h58C01

CATH Domain 4h58C01

Image of CATH 4h58C02

4h58C02

CATH Domain 4h58C02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	28 Mar, 2013	Chopped
B	28 Mar, 2013	Chopped
C	28 Mar, 2013	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4h58A01	10 Apr, 2013	3.30.200.20	Assigned
4h58A02	10 Apr, 2013	1.10.510.10	Assigned
4h58B01	10 Apr, 2013	3.30.200.20	Assigned
4h58B02	10 Apr, 2013	1.10.510.10	Assigned
4h58C01	10 Apr, 2013	3.30.200.20	Assigned
4h58C02	10 Apr, 2013	1.10.510.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf