PDB 4gvj

PDB Information

PDB4GVJ
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Lead identification of novel and selective TYK2 inhibitors.
Liang, J., Tsui, V., Van Abbema, A., Bao, L., Barrett, K., Beresini, M., Berezhkovskiy, L., Blair, W.S., Chang, C., Driscoll, J., Eigenbrot, C., Ghilardi, N., Gibbons, P., Halladay, J., Johnson, A., Kohli, P.B., Lai, Y., Liimatta, M., Mantik, P., Menghrajani, K., Murray, J., Sambrone, A., Xiao, Y., Shia, S., Shin, Y., Smith, J., Sohn, S., Stanley, M., Ultsch, M., Zhang, B., Wu, L.C., Magnuson, S.
Eur.J.Med.Chem.
HeaderHydrolase
Released2012-08-30
Resolution2.030
CATH Insert Date01 Sep, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 02 Sep, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4gvjA01 04 Sep, 2013 3.30.200.20 Assigned
4gvjA02 04 Sep, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P29597 TYK2_HUMAN Homo sapiens Non-receptor tyrosine-protein kinase TYK2