PDB 4grw

PDB Links
Overview

PDB Information

PDB	4GRW
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Neutralization of Human Interleukin 23 by Multivalent Nanobodies Explained by the Structure of Cytokine-Nanobody Complex. Desmyter, A., Spinelli, S., Boutton, C., Saunders, M., Blachetot, C., de Haard, H., Denecker, G., Van Roy, M., Cambillau, C., Rommelaere, H. Front Immunol
Header	Immune System
Released	2012-08-27
Resolution	2.550
CATH Insert Date	23 Feb, 2014

PDB Images (25)

4grw

PDB 4grw

4grwA

PDB Chain 4grwA

4grwB

PDB Chain 4grwB

4grwC

PDB Chain 4grwC

4grwD

PDB Chain 4grwD

4grwE

PDB Chain 4grwE

4grwF

PDB Chain 4grwF

4grwG

PDB Chain 4grwG

4grwH

PDB Chain 4grwH

4grwI

PDB Chain 4grwI

4grwJ

PDB Chain 4grwJ

4grwA00

CATH Domain 4grwA00

4grwB01

CATH Domain 4grwB01

4grwB02

CATH Domain 4grwB02

4grwB03

CATH Domain 4grwB03

4grwC00

CATH Domain 4grwC00

4grwD01

CATH Domain 4grwD01

4grwD02

CATH Domain 4grwD02

4grwD03

CATH Domain 4grwD03

4grwE00

CATH Domain 4grwE00

4grwF00

CATH Domain 4grwF00

4grwG00

CATH Domain 4grwG00

4grwH00

CATH Domain 4grwH00

4grwI00

CATH Domain 4grwI00

4grwJ00

CATH Domain 4grwJ00

PDB Prints

PDB Chains (10)

Chain ID	Date inserted into CATH	CATH Status
A	24 Feb, 2014	Chopped
B	24 Feb, 2014	Chopped
C	24 Feb, 2014	Chopped
D	24 Feb, 2014	Chopped
E	24 Feb, 2014	Chopped
F	24 Feb, 2014	Chopped
G	24 Feb, 2014	Chopped
H	24 Feb, 2014	Chopped
I	24 Feb, 2014	Chopped
J	24 Feb, 2014	Chopped

CATH Domains (14)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4grwA00	07 Mar, 2014	1.20.1250.10	Assigned
4grwB01	07 Mar, 2014	2.60.40.10	Assigned
4grwB02	07 Mar, 2014	2.60.40.10	Assigned
4grwB03	07 Mar, 2014	2.60.40.10	Assigned
4grwC00	07 Mar, 2014	1.20.1250.10	Assigned
4grwD01	07 Mar, 2014	2.60.40.10	Assigned
4grwD02	07 Mar, 2014	2.60.40.10	Assigned
4grwD03	07 Mar, 2014	2.60.40.10	Assigned
4grwE00	07 Mar, 2014	2.60.40.10	Assigned
4grwF00	07 Mar, 2014	2.60.40.10	Assigned
4grwG00	07 Mar, 2014	2.60.40.10	Assigned
4grwH00	07 Mar, 2014	2.60.40.10	Assigned
4grwI00	07 Mar, 2014	2.60.40.10	Assigned
4grwJ00	07 Mar, 2014	2.60.40.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q9NPF7	IL23A_HUMAN	Homo sapiens	Interleukin-23 subunit alpha
Q9NPF7	IL23A_HUMAN	Homo sapiens	Interleukin-23 subunit alpha
P29460	IL12B_HUMAN	Homo sapiens	Interleukin-12 subunit beta
P29460	IL12B_HUMAN	Homo sapiens	Interleukin-12 subunit beta

Network disruptions