PDB 4glx

PDB Information

PDB4GLX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEscherichia coli
Primary Citation
Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity.
Surivet, J.P., Lange, R., Hubschwerlen, C., Keck, W., Specklin, J.L., Ritz, D., Bur, D., Locher, H., Seiler, P., Strasser, D.S., Prade, L., Kohl, C., Schmitt, C., Chapoux, G., Ilhan, E., Ekambaram, N., Athanasiou, A., Knezevic, A., Sabato, D., Chambovey, A., Gaertner, M., Enderlin, M., Boehme, M., Sippel, V., Wyss, P.
Bioorg.Med.Chem.Lett.
HeaderLigase/Ligase Inhibitor/Dna
Released2012-08-15
Resolution1.900
CATH Insert Date04 Nov, 2012

PDB Images (12)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Rejected
C 05 Nov, 2012 Rejected
D 05 Nov, 2012 Rejected

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
4glxA01 09 Sep, 2013 1.10.287.610 Assigned
4glxA02 09 Sep, 2013 3.30.470.30 Assigned
4glxA03 09 Sep, 2013 3.30.1490.70 Assigned
4glxA04 09 Sep, 2013 2.40.50.140 Assigned
4glxA05 09 Sep, 2013 6.20.10.30 Assigned
4glxA06 09 Sep, 2013 1.10.150.20 Assigned
4glxA07 09 Sep, 2013 1.10.150.20 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P15042 DNLJ_ECOLI Escherichia coli K-12 DNA ligase