PDB 4glx

PDB Links
Overview

PDB Information

PDB	4GLX
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Escherichia coli
Primary Citation	Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity. Surivet, J.P., Lange, R., Hubschwerlen, C., Keck, W., Specklin, J.L., Ritz, D., Bur, D., Locher, H., Seiler, P., Strasser, D.S., Prade, L., Kohl, C., Schmitt, C., Chapoux, G., Ilhan, E., Ekambaram, N., Athanasiou, A., Knezevic, A., Sabato, D., Chambovey, A., Gaertner, M., Enderlin, M., Boehme, M., Sippel, V., Wyss, P. Bioorg.Med.Chem.Lett.
Header	Ligase/Ligase Inhibitor/Dna
Released	2012-08-15
Resolution	1.900
CATH Insert Date	04 Nov, 2012

PDB Images (12)

Image of CATH 4glx

4glx

PDB 4glx

Image of CATH 4glxA

4glxA

PDB Chain 4glxA

Image of CATH 4glxB

4glxB

PDB Chain 4glxB

Image of CATH 4glxC

4glxC

PDB Chain 4glxC

Image of CATH 4glxD

4glxD

PDB Chain 4glxD

Image of CATH 4glxA01

4glxA01

CATH Domain 4glxA01

Image of CATH 4glxA02

4glxA02

CATH Domain 4glxA02

Image of CATH 4glxA03

4glxA03

CATH Domain 4glxA03

Image of CATH 4glxA04

4glxA04

CATH Domain 4glxA04

Image of CATH 4glxA05

4glxA05

CATH Domain 4glxA05

Image of CATH 4glxA06

4glxA06

CATH Domain 4glxA06

Image of CATH 4glxA07

4glxA07

CATH Domain 4glxA07

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	05 Nov, 2012	Chopped
B	05 Nov, 2012	Rejected
C	05 Nov, 2012	Rejected
D	05 Nov, 2012	Rejected

CATH Domains (7)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4glxA01	09 Sep, 2013	1.10.287.610	Assigned
4glxA02	09 Sep, 2013	3.30.470.30	Assigned
4glxA03	09 Sep, 2013	3.30.1490.70	Assigned
4glxA04	09 Sep, 2013	2.40.50.140	Assigned
4glxA05	09 Sep, 2013	6.20.10.30	Assigned
4glxA06	09 Sep, 2013	1.10.150.20	Assigned
4glxA07	09 Sep, 2013	1.10.150.20	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P15042	DNLJ_ECOLI	Escherichia coli K-12	DNA ligase