PDB 4gl9
PDB Information
| PDB | 4GL9 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Spodoptera frugiperda |
| Gene Source | Mus musculus |
| Primary Citation | SOCS3 binds specific receptor-JAK complexes to control cytokine signaling by direct kinase inhibition.
Nat.Struct.Mol.Biol.
|
| Header | Transferase/Transferase Inhibitor |
| Released | 2012-08-14 |
| Resolution | 3.900 |
| CATH Insert Date | 28 Mar, 2013 |
PDB Images (25)
4gl9
PDB 4gl9
4gl9A
PDB Chain 4gl9A
4gl9B
PDB Chain 4gl9B
4gl9C
PDB Chain 4gl9C
4gl9D
PDB Chain 4gl9D
4gl9E
PDB Chain 4gl9E
4gl9F
PDB Chain 4gl9F
4gl9G
PDB Chain 4gl9G
4gl9H
PDB Chain 4gl9H
4gl9I
PDB Chain 4gl9I
4gl9J
PDB Chain 4gl9J
4gl9K
PDB Chain 4gl9K
4gl9L
PDB Chain 4gl9L
4gl9A01
CATH Domain 4gl9A01
4gl9A02
CATH Domain 4gl9A02
4gl9B01
CATH Domain 4gl9B01
4gl9B02
CATH Domain 4gl9B02
4gl9C01
CATH Domain 4gl9C01
4gl9C02
CATH Domain 4gl9C02
4gl9D01
CATH Domain 4gl9D01
4gl9D02
CATH Domain 4gl9D02
4gl9E00
CATH Domain 4gl9E00
4gl9F00
CATH Domain 4gl9F00
4gl9G00
CATH Domain 4gl9G00
4gl9H00
CATH Domain 4gl9H00
PDB Prints
PDB Chains (12)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 28 Mar, 2013 | Chopped |
| B | 28 Mar, 2013 | Chopped |
| C | 28 Mar, 2013 | Chopped |
| D | 28 Mar, 2013 | Chopped |
| E | 28 Mar, 2013 | Chopped |
| F | 28 Mar, 2013 | Chopped |
| G | 28 Mar, 2013 | Chopped |
| H | 28 Mar, 2013 | Chopped |
| I | 28 Mar, 2013 | Rejected |
| J | 28 Mar, 2013 | Rejected |
| K | 28 Mar, 2013 | Rejected |
| L | 28 Mar, 2013 | Rejected |
CATH Domains (12)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4gl9A01 | 10 Apr, 2013 | 3.30.200.20 | Assigned |
| 4gl9A02 | 10 Apr, 2013 | 1.10.510.10 | Assigned |
| 4gl9B01 | 10 Apr, 2013 | 3.30.200.20 | Assigned |
| 4gl9B02 | 10 Apr, 2013 | 1.10.510.10 | Assigned |
| 4gl9C01 | 10 Apr, 2013 | 3.30.200.20 | Assigned |
| 4gl9C02 | 10 Apr, 2013 | 1.10.510.10 | Assigned |
| 4gl9D01 | 10 Apr, 2013 | 3.30.200.20 | Assigned |
| 4gl9D02 | 10 Apr, 2013 | 1.10.510.10 | Assigned |
| 4gl9E00 | 14 Jun, 2013 | 3.30.505.10 | Assigned |
| 4gl9F00 | 01 Jul, 2013 | 3.30.505.10 | Assigned |
| 4gl9G00 | 01 Jul, 2013 | 3.30.505.10 | Assigned |
| 4gl9H00 | 01 Jul, 2013 | 3.30.505.10 | Assigned |
UniProtKB Entries (12)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q00560 | IL6RB_MOUSE | Mus musculus | Interleukin-6 receptor subunit beta |
| O35718 | SOCS3_MOUSE | Mus musculus | Suppressor of cytokine signaling 3 |
| O35718 | SOCS3_MOUSE | Mus musculus | Suppressor of cytokine signaling 3 |
| O35718 | SOCS3_MOUSE | Mus musculus | Suppressor of cytokine signaling 3 |
| Q00560 | IL6RB_MOUSE | Mus musculus | Interleukin-6 receptor subunit beta |
| Q62120 | JAK2_MOUSE | Mus musculus | Tyrosine-protein kinase JAK2 |
| Q00560 | IL6RB_MOUSE | Mus musculus | Interleukin-6 receptor subunit beta |
| Q62120 | JAK2_MOUSE | Mus musculus | Tyrosine-protein kinase JAK2 |
| Q00560 | IL6RB_MOUSE | Mus musculus | Interleukin-6 receptor subunit beta |
| Q62120 | JAK2_MOUSE | Mus musculus | Tyrosine-protein kinase JAK2 |
| O35718 | SOCS3_MOUSE | Mus musculus | Suppressor of cytokine signaling 3 |
| Q62120 | JAK2_MOUSE | Mus musculus | Tyrosine-protein kinase JAK2 |
