PDB 4gae

PDB Information

PDB4GAE
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum
Primary Citation
Antimalarial and Structural Studies of Pyridine-containing Inhibitors of 1-Deoxyxylulose-5-phosphate Reductoisomerase.
Xue, J., Diao, J., Cai, G., Deng, L., Zheng, B., Yao, Y., Song, Y.
ACS Med Chem Lett
HeaderIsomerase/Isomerase Inhibitor
Released2012-07-25
Resolution2.300
CATH Insert Date28 Mar, 2013

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped
B 28 Mar, 2013 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4gaeA01 10 Apr, 2013 3.40.50.720 Assigned
4gaeA02 10 Apr, 2013 Holding pen
4gaeA03 10 Apr, 2013 1.10.1740.10 Assigned
4gaeB01 10 Apr, 2013 3.40.50.720 Assigned
4gaeB02 10 Apr, 2013 Holding pen
4gaeB03 10 Apr, 2013 1.10.1740.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O96693 DXR_PLAFX Plasmodium falciparum HB3 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic
O96693 DXR_PLAFX Plasmodium falciparum HB3 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic