PDB 4g7g

PDB Links
Overview

PDB Information

PDB	4G7G
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Trypanosoma brucei
Primary Citation	VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis. Lepesheva, G.I., Hargrove, T.Y., Rachakonda, G., Wawrzak, Z., Pomel, S., Cojean, S., Nde, P.N., Nes, W.D., Locuson, C.W., Calcutt, M.W., Waterman, M.R., Daniels, J.S., Loiseau, P.M., Villalta, F. J Infect Dis
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2012-07-20
Resolution	2.050
CATH Insert Date	04 Aug, 2013

PDB Images (9)

Image of CATH 4g7g

4g7g

PDB 4g7g

Image of CATH 4g7gA

4g7gA

PDB Chain 4g7gA

Image of CATH 4g7gB

4g7gB

PDB Chain 4g7gB

Image of CATH 4g7gC

4g7gC

PDB Chain 4g7gC

Image of CATH 4g7gD

4g7gD

PDB Chain 4g7gD

Image of CATH 4g7gA00

4g7gA00

CATH Domain 4g7gA00

Image of CATH 4g7gB00

4g7gB00

CATH Domain 4g7gB00

Image of CATH 4g7gC00

4g7gC00

CATH Domain 4g7gC00

Image of CATH 4g7gD00

4g7gD00

CATH Domain 4g7gD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	05 Aug, 2013	Chopped
B	05 Aug, 2013	Chopped
C	05 Aug, 2013	Chopped
D	05 Aug, 2013	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4g7gA00	14 Aug, 2013	1.10.630.10	Assigned
4g7gB00	14 Aug, 2013	1.10.630.10	Assigned
4g7gC00	14 Aug, 2013	1.10.630.10	Assigned
4g7gD00	14 Aug, 2013	1.10.630.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q385E8	Q385E8_TRYB2	Trypanosoma brucei brucei TREU927	Lanosterol 14-alpha-demethylase
Q385E8	Q385E8_TRYB2	Trypanosoma brucei brucei TREU927	Lanosterol 14-alpha-demethylase
Q385E8	Q385E8_TRYB2	Trypanosoma brucei brucei TREU927	Lanosterol 14-alpha-demethylase
Q385E8	Q385E8_TRYB2	Trypanosoma brucei brucei TREU927	Lanosterol 14-alpha-demethylase