PDB 4g3j

PDB Links
Overview

PDB Information

PDB	4G3J
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Trypanosoma brucei
Primary Citation	VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis. Lepesheva, G.I., Hargrove, T.Y., Rachakonda, G., Wawrzak, Z., Pomel, S., Cojean, S., Nde, P.N., Nes, W.D., Locuson, C.W., Calcutt, M.W., Waterman, M.R., Daniels, J.S., Loiseau, P.M., Villalta, F. J Infect Dis
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2012-07-14
Resolution	1.830
CATH Insert Date	04 Aug, 2013

PDB Images (9)

Image of CATH 4g3j

4g3j

PDB 4g3j

Image of CATH 4g3jA

4g3jA

PDB Chain 4g3jA

Image of CATH 4g3jB

4g3jB

PDB Chain 4g3jB

Image of CATH 4g3jC

4g3jC

PDB Chain 4g3jC

Image of CATH 4g3jD

4g3jD

PDB Chain 4g3jD

Image of CATH 4g3jA00

4g3jA00

CATH Domain 4g3jA00

Image of CATH 4g3jB00

4g3jB00

CATH Domain 4g3jB00

Image of CATH 4g3jC00

4g3jC00

CATH Domain 4g3jC00

Image of CATH 4g3jD00

4g3jD00

CATH Domain 4g3jD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	05 Aug, 2013	Chopped
B	05 Aug, 2013	Chopped
C	05 Aug, 2013	Chopped
D	05 Aug, 2013	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4g3jA00	14 Aug, 2013	1.10.630.10	Assigned
4g3jB00	14 Aug, 2013	1.10.630.10	Assigned
4g3jC00	14 Aug, 2013	1.10.630.10	Assigned
4g3jD00	13 Aug, 2013	1.10.630.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q385E8	Q385E8_TRYB2	Trypanosoma brucei brucei TREU927	Lanosterol 14-alpha-demethylase
Q385E8	Q385E8_TRYB2	Trypanosoma brucei brucei TREU927	Lanosterol 14-alpha-demethylase
Q385E8	Q385E8_TRYB2	Trypanosoma brucei brucei TREU927	Lanosterol 14-alpha-demethylase
Q385E8	Q385E8_TRYB2	Trypanosoma brucei brucei TREU927	Lanosterol 14-alpha-demethylase