PDB Information

PDB4G0V
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Wu, C.C., Li, Y.C., Wang, Y.R., Li, T.K., Chan, N.L.
Nucleic Acids Res.
HeaderIsomerase/Dna/Isomerase Inhibitor
Released2012-07-10
Resolution2.55
CATH Insert Date04 Aug, 2013

PDB Images (15)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 05 Aug, 2013 Chopped
B 05 Aug, 2013 Chopped
C 05 Aug, 2013 Rejected
D 05 Aug, 2013 Rejected
E 05 Aug, 2013 Rejected
F 05 Aug, 2013 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4g0vA01 10 Oct, 2013 3.40.50.670 Assigned
4g0vA02 10 Oct, 2013 3.90.199.10 Assigned
4g0vA03 10 Oct, 2013 3.30.1360.40 Assigned
4g0vA04 10 Oct, 2013 1.10.268.10 Assigned
4g0vB01 10 Oct, 2013 3.40.50.670 Assigned
4g0vB02 10 Oct, 2013 3.90.199.10 Assigned
4g0vB03 10 Oct, 2013 3.30.1360.40 Assigned
4g0vB04 10 Oct, 2013 1.10.268.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q02880 TOP2B_HUMAN Homo sapiens DNA topoisomerase 2-beta
Q02880 TOP2B_HUMAN Homo sapiens DNA topoisomerase 2-beta