PDB 4fz7

PDB Information

PDB4FZ7
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Using ovality to predict nonmutagenic, orally efficacious pyridazine amides as cell specific spleen tyrosine kinase inhibitors.
Lucas, M.C., Bhagirath, N., Chiao, E., Goldstein, D.M., Hermann, J.C., Hsu, P.Y., Kirchner, S., Kennedy-Smith, J.J., Kuglstatter, A., Lukacs, C., Menke, J., Niu, L., Padilla, F., Peng, Y., Polonchuk, L., Railkar, A., Slade, M., Soth, M., Xu, D., Yadava, P., Yee, C., Zhou, M., Liao, C.
J. Med. Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-07-06
Resolution1.750
CATH Insert Date04 Aug, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Aug, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4fz7A01 13 Aug, 2013 3.30.200.20 Assigned
4fz7A02 13 Aug, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P43405 KSYK_HUMAN Homo sapiens Tyrosine-protein kinase SYK