PDB 4fob

PDB Information

PDB4FOB
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
The Discovery and Optimization of a Novel Class of Potent, Selective, and Orally Bioavailable Anaplastic Lymphoma Kinase (ALK) Inhibitors with Potential Utility for the Treatment of Cancer.
Lewis, R.T., Bode, C.M., Choquette, D.M., Potashman, M., Romero, K., Stellwagen, J.C., Teffera, Y., Moore, E., Whittington, D.A., Chen, H., Epstein, L.F., Emkey, R., Andrews, P.S., Yu, V.L., Saffran, D.C., Xu, M., Drew, A., Merkel, P., Szilvassy, S., Brake, R.L.
J.Med.Chem.
HeaderTransferase/Inhibitor
Released2012-06-20
Resolution1.900
CATH Insert Date04 Nov, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4fobA01 10 Nov, 2012 3.30.200.20 Assigned
4fobA02 10 Nov, 2012 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9UM73 ALK_HUMAN Homo sapiens ALK tyrosine kinase receptor