PDB 4fk3

PDB Links
Overview

PDB Information

PDB	4FK3
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Tsai, J., T Lee, J., Wang, W., Zhang, J., Cho, H., Mamo, S., Bremer, R., Gillette, S., Kong, J., Haass, N.K. Proc.Natl.Acad.Sci.USA
Header	Transferase/Transferase Inhibitor
Released	2012-06-12
Resolution	2.650
CATH Insert Date	04 Nov, 2012

PDB Images (7)

Image of CATH 4fk3

4fk3

PDB 4fk3

Image of CATH 4fk3A

4fk3A

PDB Chain 4fk3A

Image of CATH 4fk3B

4fk3B

PDB Chain 4fk3B

Image of CATH 4fk3A01

4fk3A01

CATH Domain 4fk3A01

Image of CATH 4fk3A02

4fk3A02

CATH Domain 4fk3A02

Image of CATH 4fk3B01

4fk3B01

CATH Domain 4fk3B01

Image of CATH 4fk3B02

4fk3B02

CATH Domain 4fk3B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Nov, 2012	Chopped
B	05 Nov, 2012	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4fk3A01	10 Nov, 2012	3.30.200.20	Assigned
4fk3A02	10 Nov, 2012	1.10.510.10	Assigned
4fk3B01	10 Nov, 2012	3.30.200.20	Assigned
4fk3B02	10 Nov, 2012	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf