PDB Information

PDB4FGY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor Gamma (PPAR-gamma) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes.
Zheng, W., Feng, X., Qiu, L., Pan, Z., Wang, R., Lin, S., Hou, D., Jin, L., Li, Y.
Diabetologia
HeaderTranscription/Transferase/Antibiotic
Released2012-06-05
Resolution2.840
CATH Insert Date28 Mar, 2013

PDB Images (4)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped
B 28 Mar, 2013 Rejected

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4fgyA00 10 Apr, 2013 1.10.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P37231 PPARG_HUMAN Homo sapiens Peroxisome proliferator-activated receptor gamma
Q15788 NCOA1_HUMAN Homo sapiens Nuclear receptor coactivator 1