PDB 4fcb

PDB Links
Overview

PDB Information

PDB	4FCB
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Novel triazines as potent and selective phosphodiesterase 10A inhibitors. Malamas, M.S., Stange, H., Schindler, R., Lankau, H.J., Grunwald, C., Langen, B., Egerland, U., Hage, T., Ni, Y., Erdei, J., Fan, K.Y., Parris, K., Marquis, K.L., Grauer, S., Brennan, J., Navarra, R., Graf, R., Harrison, B.L., Robichaud, A., Kronbach, T., Pangalos, M.N., Brandon, N.J., Hoefgen, N. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2012-05-24
Resolution	2.100
CATH Insert Date	04 Nov, 2012

PDB Images (5)

Image of CATH 4fcb

4fcb

PDB 4fcb

Image of CATH 4fcbA

4fcbA

PDB Chain 4fcbA

Image of CATH 4fcbB

4fcbB

PDB Chain 4fcbB

Image of CATH 4fcbA00

4fcbA00

CATH Domain 4fcbA00

Image of CATH 4fcbB00

4fcbB00

CATH Domain 4fcbB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Nov, 2012	Chopped
B	05 Nov, 2012	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4fcbA00	08 Feb, 2013	1.10.1300.10	Assigned
4fcbB00	08 Feb, 2013	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A