PDB 4fc0

PDB Links
Overview

PDB Information

PDB	4FC0
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives. Hirose, M., Okaniwa, M., Miyazaki, T., Imada, T., Ohashi, T., Tanaka, Y., Arita, T., Yabuki, M., Kawamoto, T., Tsutsumi, S., Sumita, A., Takagi, T., Sang, B.C., Yano, J., Aertgeerts, K., Yoshida, S., Ishikawa, T. Bioorg.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2012-05-23
Resolution	2.950
CATH Insert Date	02 Feb, 2014

PDB Images (7)

Image of CATH 4fc0

4fc0

PDB 4fc0

Image of CATH 4fc0A

4fc0A

PDB Chain 4fc0A

Image of CATH 4fc0B

4fc0B

PDB Chain 4fc0B

Image of CATH 4fc0A01

4fc0A01

CATH Domain 4fc0A01

Image of CATH 4fc0A02

4fc0A02

CATH Domain 4fc0A02

Image of CATH 4fc0B01

4fc0B01

CATH Domain 4fc0B01

Image of CATH 4fc0B02

4fc0B02

CATH Domain 4fc0B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	03 Feb, 2014	Chopped
B	03 Feb, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4fc0A01	07 Mar, 2014	3.30.200.20	Assigned
4fc0A02	07 Mar, 2014	1.10.510.10	Assigned
4fc0B01	07 Mar, 2014	3.30.200.20	Assigned
4fc0B02	07 Mar, 2014	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf