PDB 4ezh

PDB Information

PDB4EZH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Kruidenier, L., Chung, C.W., Cheng, Z., Liddle, J., Che, K., Joberty, G., Bantscheff, M., Bountra, C., Bridges, A., Diallo, H., Eberhard, D., Hutchinson, S., Jones, E., Katso, R., Leveridge, M., Mander, P.K., Mosley, J., Ramirez-Molina, C., Rowland, P., Schofield, C.J., Sheppard, R.J., Smith, J.E., Swales, C., Tanner, R., Thomas, P., Tumber, A., Drewes, G., Oppermann, U., Patel, D.J., Lee, K., Wilson, D.M.
Nature
HeaderOxidoreductase
Released2012-05-02
Resolution2.520
CATH Insert Date04 Nov, 2012

PDB Images (11)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped
C 05 Nov, 2012 Rejected
D 05 Nov, 2012 Rejected

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4ezhA01 08 Oct, 2013 2.60.120.650 Assigned
4ezhA02 08 Oct, 2013 1.20.58.1370 Assigned
4ezhA03 08 Oct, 2013 2.10.110.20 Assigned
4ezhB01 08 Oct, 2013 2.60.120.650 Assigned
4ezhB02 08 Oct, 2013 1.20.58.1370 Assigned
4ezhB03 08 Oct, 2013 2.10.110.20 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P68431 H31_HUMAN Homo sapiens Histone H3.1
Q5NCY0 KDM6B_MOUSE Mus musculus Lysine-specific demethylase 6B
Q5NCY0 KDM6B_MOUSE Mus musculus Lysine-specific demethylase 6B
P68431 H31_HUMAN Homo sapiens Histone H3.1