PDB Information

PDB4EWQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
A Selective and Brain Penetrant p38 alpha MAPK Inhibitor Candidate for Neurologic and Neuropsychiatric Disorders That Attenuates Neuroinflammation and Cognitive Dysfunction.
Roy, S.M., Minasov, G., Arancio, O., Chico, L.W., Van Eldik, L.J., Anderson, W.F., Pelletier, J.C., Watterson, D.M.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-04-27
Resolution2.100
CATH Insert Date04 Nov, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4ewqA01 10 Nov, 2012 3.30.200.20 Assigned
4ewqA02 10 Nov, 2012 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14