PDB 4ewo

PDB Information

PDB4EWO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and synthesis of potent hydroxyethylamine (HEA) BACE-1 inhibitors carrying prime side 4,5,6,7-tetrahydrobenzazole and 4,5,6,7-tetrahydropyridinoazole templates.
Sund, C., Belda, O., Borkakoti, N., Lindberg, J., Derbyshire, D., Vrang, L., Hamelink, E., Hgren, C., Woestenenk, E., Wikstrom, K., Eneroth, A., Lindstrom, E., Kalayanov, G.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-04-27
Resolution1.800
CATH Insert Date04 Nov, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4ewoA01 10 Nov, 2012 2.40.70.10 Assigned
4ewoA02 10 Nov, 2012 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
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