PDB 4erf

PDB Information

PDB4ERF
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-based design of novel inhibitors of the MDM2-p53 interaction.
Rew, Y., Sun, D., Gonzalez-Lopez De Turiso, F., Bartberger, M.D., Beck, H.P., Canon, J., Chen, A., Chow, D., Deignan, J., Fox, B.M., Gustin, D., Huang, X., Jiang, M., Jiao, X., Jin, L., Kayser, F., Kopecky, D.J., Li, Y., Lo, M.C., Long, A.M., Michelsen, K., Oliner, J.D., Osgood, T., Ragains, M., Saiki, A.Y., Schneider, S., Toteva, M., Yakowec, P., Yan, X., Ye, Q., Yu, D., Zhao, X., Zhou, J., Medina, J.C., Olson, S.H.
J.Med.Chem.
HeaderLigase/Ligase Inhibitor
Released2012-04-20
Resolution2.000
CATH Insert Date27 May, 2012

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
C 28 May, 2012 Chopped
E 28 May, 2012 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4erfA00 08 Jun, 2012 1.10.245.10 Assigned
4erfC00 08 Jun, 2012 1.10.245.10 Assigned
4erfE00 08 Jun, 2012 1.10.245.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2