PDB 4ehe

PDB Links
Overview

PDB Information

PDB	4EHE
Method	X-RAY DIFFRACTION
Host Organism	Trichoplusia ni
Gene Source	Homo sapiens
Primary Citation	Potent and selective aminopyrimidine-based B-raf inhibitors with favorable physicochemical and pharmacokinetic properties. Mathieu, S., Gradl, S.N., Ren, L., Wen, Z., Aliagas, I., Gunzner-Toste, J., Lee, W., Pulk, R., Zhao, G., Alicke, B., Boggs, J.W., Buckmelter, A.J., Choo, E.F., Dinkel, V., Gloor, S.L., Gould, S.E., Hansen, J.D., Hastings, G., Hatzivassiliou, G., Laird, E.R., Moreno, D., Ran, Y., Voegtli, W.C., Wenglowsky, S., Grina, J., Rudolph, J. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2012-04-02
Resolution	3.300
CATH Insert Date	07 Jul, 2013

PDB Images (7)

Image of CATH 4ehe

4ehe

PDB 4ehe

Image of CATH 4eheA

4eheA

PDB Chain 4eheA

Image of CATH 4eheB

4eheB

PDB Chain 4eheB

Image of CATH 4eheA01

4eheA01

CATH Domain 4eheA01

Image of CATH 4eheA02

4eheA02

CATH Domain 4eheA02

Image of CATH 4eheB01

4eheB01

CATH Domain 4eheB01

Image of CATH 4eheB02

4eheB02

CATH Domain 4eheB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	08 Jul, 2013	Chopped
B	08 Jul, 2013	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4eheA01	09 Aug, 2013	3.30.200.20	Assigned
4eheA02	09 Aug, 2013	1.10.510.10	Assigned
4eheB01	09 Aug, 2013	3.30.200.20	Assigned
4eheB02	09 Aug, 2013	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf