×
Network disruptions
We have been experiencing disruptions on our local network which has affected the stability of these web pages.
We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.
PDB Information
| PDB | 4EF8 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Leishmania major |
| Primary Citation |
Target sites for the design of anti-trypanosomatid drugs based on the structure of dihydroorotate dehydrogenase.
Pinheiro, M.P., Emery, F.S., Nonato, M.C.
Curr.Pharm.Des.
|
| Header | Oxidoreductase/Oxidoreductase Inhibitor |
| Released | 2012-03-29 |
| Resolution | 1.560 |
| CATH Insert Date | 30 Dec, 2012 |
PDB Images (7)
4ef8A01
CATH Domain 4ef8A01
4ef8A02
CATH Domain 4ef8A02
4ef8B01
CATH Domain 4ef8B01
4ef8B02
CATH Domain 4ef8B02
PDB Chains (2)
| Chain ID | Date inserted into CATH | CATH Status |
| A | 31 Dec, 2012 | Chopped
|
| B | 31 Dec, 2012 | Chopped
|
CATH Domains (4)
UniProtKB Entries (2)
| Accession |
Gene ID |
Taxon |
Description |
| Q4QEW7 |
Q4QEW7_LEIMA |
Leishmania major |
Dihydroorotate dehydrogenase (fumarate) |
| Q4QEW7 |
Q4QEW7_LEIMA |
Leishmania major |
Dihydroorotate dehydrogenase (fumarate) |