PDB 4e6d

PDB Links
Overview

PDB Information

PDB	4E6D
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Identification of Imidazo-Pyrrolopyridines as Novel and Potent JAK1 Inhibitors. Kulagowski, J.J., Blair, W., Bull, R.J., Chang, C., Deshmukh, G., Dyke, H.J., Eigenbrot, C., Ghilardi, N., Gibbons, P., Harrison, T.K., Hewitt, P.R., Liimatta, M., Hurley, C.A., Johnson, A., Johnson, T., Kenny, J.R., Bir Kohli, P., Maxey, R.J., Mendonca, R., Mortara, K., Murray, J., Narukulla, R., Shia, S., Steffek, M., Ubhayakar, S., Ultsch, M., van Abbema, A., Ward, S.I., Waszkowycz, B., Zak, M. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2012-03-15
Resolution	2.220
CATH Insert Date	03 Jun, 2012

PDB Images (7)

Image of CATH 4e6d

4e6d

PDB 4e6d

Image of CATH 4e6dA

4e6dA

PDB Chain 4e6dA

Image of CATH 4e6dB

4e6dB

PDB Chain 4e6dB

Image of CATH 4e6dA01

4e6dA01

CATH Domain 4e6dA01

Image of CATH 4e6dA02

4e6dA02

CATH Domain 4e6dA02

Image of CATH 4e6dB01

4e6dB01

CATH Domain 4e6dB01

Image of CATH 4e6dB02

4e6dB02

CATH Domain 4e6dB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	03 Jun, 2012	Chopped
B	03 Jun, 2012	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4e6dA01	08 Jun, 2012	3.30.200.20	Assigned
4e6dA02	08 Jun, 2012	1.10.510.10	Assigned
4e6dB01	08 Jun, 2012	3.30.200.20	Assigned
4e6dB02	08 Jun, 2012	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2