PDB 4e20

PDB Information

PDB4E20
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceMus musculus
Primary Citation
Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor.
Argiriadi, M.A., Goedken, E.R., Banach, D., Borhani, D.W., Burchat, A., Dixon, R.W., Marcotte, D., Overmeyer, G., Pivorunas, V., Sadhukhan, R., Sousa, S., Moore, N.S., Tomlinson, M., Voss, J., Wang, L., Wishart, N., Woller, K., Talanian, R.V.
Bmc Struct.Biol.
HeaderTransferase/Transferase Inhibitor
Released2012-03-07
Resolution2.600
CATH Insert Date04 Nov, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4e20A01 10 Nov, 2012 3.30.200.20 Assigned
4e20A02 10 Nov, 2012 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9R117 TYK2_MOUSE Mus musculus Non-receptor tyrosine-protein kinase TYK2