PDB Information

PDB4DXJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceTrypanosoma cruzi
Primary Citation
Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
Aripirala, S., Szajnman, S.H., Jakoncic, J., Rodriguez, J.B., Docampo, R., Gabelli, S.B., Amzel, L.M.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-02-27
Resolution2.350
CATH Insert Date27 Jan, 2013

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 28 Jan, 2013 Chopped
B 28 Jan, 2013 Chopped
C 28 Jan, 2013 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4dxjA00 01 Feb, 2013 1.10.600.10 Assigned
4dxjB00 01 Feb, 2013 1.10.600.10 Assigned
4dxjC00 01 Feb, 2013 1.10.600.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
Q95WL3 Q95WL3_TRYCR Trypanosoma cruzi Farnesyl pyrophosphate synthase
Q95WL3 Q95WL3_TRYCR Trypanosoma cruzi Farnesyl pyrophosphate synthase
Q95WL3 Q95WL3_TRYCR Trypanosoma cruzi Farnesyl pyrophosphate synthase