PDB 4dwk

PDB Information

PDB4DWK
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-beta hydrolysis.
Charton, J., Gauriot, M., Guo, Q., Hennuyer, N., Marechal, X., Dumont, J., Hamdane, M., Pottiez, V., Landry, V., Sperandio, O., Flipo, M., Buee, L., Staels, B., Leroux, F., Tang, W.J., Deprez, B., Deprez-Poulain, R.
Eur.J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-02-24
Resolution3.000
CATH Insert Date07 Jul, 2013

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4dwkA01 31 Aug, 2013 3.30.830.10 Assigned
4dwkA02 31 Aug, 2013 3.30.830.10 Assigned
4dwkA03 31 Aug, 2013 3.30.830.10 Assigned
4dwkA04 31 Aug, 2013 3.30.830.10 Assigned
4dwkB01 31 Aug, 2013 3.30.830.10 Assigned
4dwkB02 31 Aug, 2013 3.30.830.10 Assigned
4dwkB03 31 Aug, 2013 3.30.830.10 Assigned
4dwkB04 31 Aug, 2013 3.30.830.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme