PDB Information

PDB4DW6
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMycobacterium tuberculosis
Primary Citation
Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis.
Flipo, M., Willand, N., Lecat-Guillet, N., Hounsou, C., Desroses, M., Leroux, F., Lens, Z., Villeret, V., Wohlkonig, A., Wintjens, R., Christophe, T., Kyoung Jeon, H., Locht, C., Brodin, P., Baulard, A.R., Deprez, B.
J.Med.Chem.
HeaderTranscription/Inhibitor
Released2012-02-24
Resolution2.000
CATH Insert Date07 Jul, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4dw6A01 08 Aug, 2013 1.10.10.60 Assigned
4dw6A02 08 Aug, 2013 1.10.357.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis H37Rv HTH-type transcriptional regulator EthR