PDB 4dpf
PDB Information
| PDB | 4DPF |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Highly potent macrocyclic BACE-1 inhibitors incorporating a hydroxyethylamine core: design, synthesis and X-ray crystal structures of enzyme inhibitor complexes.
Bioorg.Med.Chem.
|
| Header | Hydrolase/Hydrolase Inhibitor |
| Released | 2012-02-13 |
| Resolution | 1.800 |
| CATH Insert Date | 04 Nov, 2012 |
PDB Prints
PDB Chains (1)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 05 Nov, 2012 | Chopped |
CATH Domains (2)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4dpfA01 | 10 Nov, 2012 | 2.40.70.10 | Assigned |
| 4dpfA02 | 10 Nov, 2012 | 2.40.70.10 | Assigned |
UniProtKB Entries (1)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P56817 | BACE1_HUMAN | Homo sapiens | Beta-secretase 1 |
