PDB Information

PDB4DPD
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum
Primary Citation
Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target
Yuthavong, Y., Tarnchompoo, B., Vilaivan, T., Chitnumsub, P., Kamchonwongpaisan, S., Charman, S.A., McLennan, D.N., White, K.L., Vivas, L., Bongard, E., Thongphanchang, C., Taweechai, S., Vanichtanankul, J., Rattanajak, R., Arwon, U., Fantauzzi, P., Yuvaniyama, J., Charman, W.N., Matthews, D.
Proc.Natl.Acad.Sci.USA
HeaderOxidoreductase, Transferase
Released2012-02-13
Resolution2.500
CATH Insert Date18 Nov, 2012

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 19 Nov, 2012 Chopped
B 19 Nov, 2012 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4dpdA01 30 Aug, 2013 3.40.430.10 Assigned
4dpdA02 30 Aug, 2013 6.10.250.2210 Assigned
4dpdA03 30 Aug, 2013 3.30.572.10 Assigned
4dpdB01 30 Aug, 2013 3.40.430.10 Assigned
4dpdB02 30 Aug, 2013 6.10.250.2210 Assigned
4dpdB03 30 Aug, 2013 3.30.572.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
A7UD81 A7UD81_PLAFA Plasmodium falciparum Bifunctional dihydrofolate reductase-thymidylate synthase
A7UD81 A7UD81_PLAFA Plasmodium falciparum Bifunctional dihydrofolate reductase-thymidylate synthase