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PDB Information
| PDB | 4DIJ |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation |
The central valine concept provides an entry in a new class of non peptide inhibitors of the p53-MDM2 interaction.
Furet, P., Chene, P., De Pover, A., Valat, T.S., Lisztwan, J.H., Kallen, J., Masuya, K.
Bioorg.Med.Chem.Lett.
|
| Header | Ligase/Ligase Inhibitor |
| Released | 2012-01-31 |
| Resolution | 1.900 |
| CATH Insert Date | 27 May, 2012 |
PDB Images (5)
4dijA00
CATH Domain 4dijA00
4dijB00
CATH Domain 4dijB00
PDB Chains (2)
| Chain ID | Date inserted into CATH | CATH Status |
| A | 28 May, 2012 | Chopped
|
| B | 28 May, 2012 | Chopped
|
CATH Domains (2)
UniProtKB Entries (2)
| Accession |
Gene ID |
Taxon |
Description |
| Q00987 |
MDM2_HUMAN |
Homo sapiens |
E3 ubiquitin-protein ligase Mdm2 |
| Q00987 |
MDM2_HUMAN |
Homo sapiens |
E3 ubiquitin-protein ligase Mdm2 |