PDB 4dhf

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Overview

PDB Information

PDB	4DHF
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Structure-based design of 2,6,7-trisubstituted-7H-pyrrolo[2,3-d]pyrimidines as Aurora kinases inhibitors. Le Brazidec, J.Y., Pasis, A., Tam, B., Boykin, C., Wang, D., Marcotte, D.J., Claassen, G., Chong, J.H., Chao, J., Fan, J., Nguyen, K., Silvian, L., Ling, L., Zhang, L., Choi, M., Teng, M., Pathan, N., Zhao, S., Li, T., Taveras, A. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2012-01-27
Resolution	2.800
CATH Insert Date	04 Nov, 2012

PDB Images (7)

Image of CATH 4dhf

4dhf

PDB 4dhf

Image of CATH 4dhfA

4dhfA

PDB Chain 4dhfA

Image of CATH 4dhfB

4dhfB

PDB Chain 4dhfB

Image of CATH 4dhfA01

4dhfA01

CATH Domain 4dhfA01

Image of CATH 4dhfA02

4dhfA02

CATH Domain 4dhfA02

Image of CATH 4dhfB01

4dhfB01

CATH Domain 4dhfB01

Image of CATH 4dhfB02

4dhfB02

CATH Domain 4dhfB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Nov, 2012	Chopped
B	05 Nov, 2012	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4dhfA01	10 Nov, 2012	3.30.200.20	Assigned
4dhfA02	10 Nov, 2012	1.10.510.10	Assigned
4dhfB01	10 Nov, 2012	3.30.200.20	Assigned
4dhfB02	10 Nov, 2012	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O14965	AURKA_HUMAN	Homo sapiens	Aurora kinase A
O14965	AURKA_HUMAN	Homo sapiens	Aurora kinase A