PDB 4ddl

PDB Links
Overview

PDB Information

PDB	4DDL
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitors. Hu, E., Kunz, R.K., Rumfelt, S., Chen, N., Burli, R., Li, C., Andrews, K.L., Zhang, J., Chmait, S., Kogan, J., Lindstrom, M., Hitchcock, S.A., Treanor, J. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2012-01-18
Resolution	2.070
CATH Insert Date	27 May, 2012

PDB Images (5)

Image of CATH 4ddl

4ddl

PDB 4ddl

Image of CATH 4ddlA

4ddlA

PDB Chain 4ddlA

Image of CATH 4ddlB

4ddlB

PDB Chain 4ddlB

Image of CATH 4ddlA00

4ddlA00

CATH Domain 4ddlA00

Image of CATH 4ddlB00

4ddlB00

CATH Domain 4ddlB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	28 May, 2012	Chopped
B	28 May, 2012	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4ddlA00	08 Feb, 2013	1.10.1300.10	Assigned
4ddlB00	08 Feb, 2013	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A