PDB 4dbw

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PDB Links
Overview

PDB Information

PDB	4DBW
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Development of potent and selective indomethacin analogues for the inhibition of AKR1C3 (Type 5 17 beta-hydroxysteroid dehydrogenase/prostaglandin F synthase) in castrate-resistant prostate cancer. Liedtke, A.J., Adeniji, A.O., Chen, M., Byrns, M.C., Jin, Y., Christianson, D.W., Marnett, L.J., Penning, T.M. J.Med.Chem.
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2012-01-16
Resolution	1.800
CATH Insert Date	28 Mar, 2013

PDB Images (5)

Image of CATH 4dbw

4dbw

PDB 4dbw

Image of CATH 4dbwA

4dbwA

PDB Chain 4dbwA

Image of CATH 4dbwB

4dbwB

PDB Chain 4dbwB

Image of CATH 4dbwA00

4dbwA00

CATH Domain 4dbwA00

Image of CATH 4dbwB00

4dbwB00

CATH Domain 4dbwB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	28 Mar, 2013	Chopped
B	28 Mar, 2013	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4dbwA00	10 Apr, 2013	3.20.20.100	Assigned
4dbwB00	10 Apr, 2013	3.20.20.100	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P42330	AK1C3_HUMAN	Homo sapiens	Aldo-keto reductase family 1 member C3
P42330	AK1C3_HUMAN	Homo sapiens	Aldo-keto reductase family 1 member C3