PDB 4dbs

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PDB Links
Overview

PDB Information

PDB	4DBS
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Crystal structures of AKR1C3 containing an N-(aryl)amino-benzoate inhibitor and a bifunctional AKR1C3 inhibitor and androgen receptor antagonist. Therapeutic leads for castrate resistant prostate cancer. Chen, M., Adeniji, A.O., Twenter, B.M., Winkler, J.D., Christianson, D.W., Penning, T.M. Bioorg.Med.Chem.Lett.
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2012-01-16
Resolution	1.850
CATH Insert Date	27 May, 2012

PDB Images (5)

Image of CATH 4dbs

4dbs

PDB 4dbs

Image of CATH 4dbsA

4dbsA

PDB Chain 4dbsA

Image of CATH 4dbsB

4dbsB

PDB Chain 4dbsB

Image of CATH 4dbsA00

4dbsA00

CATH Domain 4dbsA00

Image of CATH 4dbsB00

4dbsB00

CATH Domain 4dbsB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	28 May, 2012	Chopped
B	28 May, 2012	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4dbsA00	08 Jun, 2012	3.20.20.100	Assigned
4dbsB00	08 Jun, 2012	3.20.20.100	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P42330	AK1C3_HUMAN	Homo sapiens	Aldo-keto reductase family 1 member C3
P42330	AK1C3_HUMAN	Homo sapiens	Aldo-keto reductase family 1 member C3