PDB 4d2v

PDB Links
Overview

PDB Information

PDB	4D2V
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase Johnson, C.N., Berdini, V., Beke, L., Bonnet, P., Brehmer, D., Coyle, J.E., Day, P.J., Frederickson, M., Freyne, E.J.E., Gilissen, R.A.H.J., Hamlett, C.C.F., Howard, S., Meerpoel, L., Mcmenamin, R., Patel, S., Rees, D.C., Sharff, A., Sommen, F., Wu, T., Linders, J.T.M. Acs Med.Chem.Lett.
Header	Transferase
Released	2014-05-13
Resolution	2.450
CATH Insert Date	26 Oct, 2014

PDB Images (9)

Image of CATH 4d2v

4d2v

PDB 4d2v

Image of CATH 4d2vA

4d2vA

PDB Chain 4d2vA

Image of CATH 4d2vB

4d2vB

PDB Chain 4d2vB

Image of CATH 4d2vC

4d2vC

PDB Chain 4d2vC

Image of CATH 4d2vD

4d2vD

PDB Chain 4d2vD

Image of CATH 4d2vA00

4d2vA00

CATH Domain 4d2vA00

Image of CATH 4d2vB00

4d2vB00

CATH Domain 4d2vB00

Image of CATH 4d2vC00

4d2vC00

CATH Domain 4d2vC00

Image of CATH 4d2vD00

4d2vD00

CATH Domain 4d2vD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	27 Oct, 2014	Chopped
B	27 Oct, 2014	Chopped
C	27 Oct, 2014	Chopped
D	27 Oct, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4d2vA00	02 Nov, 2014	1.10.510.10	Assigned
4d2vB00	02 Nov, 2014	1.10.510.10	Assigned
4d2vC00	02 Nov, 2014	1.10.510.10	Assigned
4d2vD00	02 Nov, 2014	1.10.510.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q14680	MELK_HUMAN	Homo sapiens	Maternal embryonic leucine zipper kinase
Q14680	MELK_HUMAN	Homo sapiens	Maternal embryonic leucine zipper kinase
Q14680	MELK_HUMAN	Homo sapiens	Maternal embryonic leucine zipper kinase
Q14680	MELK_HUMAN	Homo sapiens	Maternal embryonic leucine zipper kinase