PDB 4d08

PDB Links
Overview

PDB Information

PDB	4D08
Method	X-RAY DIFFRACTION
Host Organism	SPODOPTERA FRUGIPERDA
Gene Source	HOMO SAPIENS
Primary Citation	Structure-Based Design of a Potent, Selective, and Brain Penetrating Pde2 Inhibitor with Demonstrated Target Engagement. Buijnsters, P., De Angelis, M., Langlois, X., Rombouts, F.J.R., Sanderson, W., Tresadern, G., Ritchie, A., Trabanco, A.A., Vanhoof, G., Roosbroeck, Y.V., Andres, J. Acs Med.Chem.Lett.
Header	Hydrolase
Released	2014-04-24
Resolution	1.900
CATH Insert Date	24 Aug, 2014

PDB Images (9)

Image of CATH 4d08

4d08

PDB 4d08

Image of CATH 4d08A

4d08A

PDB Chain 4d08A

Image of CATH 4d08B

4d08B

PDB Chain 4d08B

Image of CATH 4d08C

4d08C

PDB Chain 4d08C

Image of CATH 4d08D

4d08D

PDB Chain 4d08D

Image of CATH 4d08A00

4d08A00

CATH Domain 4d08A00

Image of CATH 4d08B00

4d08B00

CATH Domain 4d08B00

Image of CATH 4d08C00

4d08C00

CATH Domain 4d08C00

Image of CATH 4d08D00

4d08D00

CATH Domain 4d08D00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	25 Aug, 2014	Chopped
B	25 Aug, 2014	Chopped
C	25 Aug, 2014	Chopped
D	25 Aug, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4d08A00	27 Aug, 2014	1.10.1300.10	Assigned
4d08B00	27 Aug, 2014	1.10.1300.10	Assigned
4d08C00	27 Aug, 2014	1.10.1300.10	Assigned
4d08D00	27 Aug, 2014	1.10.1300.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase