PDB 4cqe

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PDB Links
Overview

PDB Information

PDB	4CQE
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Optimization of Diarylthiazole B-Raf Inhibitors: Identification of a Compound Endowed with High Oral Antitumor Activity, Mitigated Herg Inhibition, and Low Paradoxical Effect. Pulici, M., Traquandi, G., Marchionni, C., Modugno, M., Lupi, R., Amboldi, N., Casale, E., Colombo, N., Corti, L., Fasolini, M., Gasparri, F., Pastori, W., Scolaro, A., Donati, D., Felder, E., Galvani, A., Isacchi, A., Pesenti, E., Ciomei, M. Chemmedchem
Header	Transferase
Released	2014-02-14
Resolution	2.300
CATH Insert Date	21 Dec, 2014

PDB Images (7)

Image of CATH 4cqe

4cqe

PDB 4cqe

Image of CATH 4cqeA

4cqeA

PDB Chain 4cqeA

Image of CATH 4cqeB

4cqeB

PDB Chain 4cqeB

Image of CATH 4cqeA01

4cqeA01

CATH Domain 4cqeA01

Image of CATH 4cqeA02

4cqeA02

CATH Domain 4cqeA02

Image of CATH 4cqeB01

4cqeB01

CATH Domain 4cqeB01

Image of CATH 4cqeB02

4cqeB02

CATH Domain 4cqeB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	22 Dec, 2014	Chopped
B	22 Dec, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4cqeA01	28 Dec, 2014	3.30.200.20	Assigned
4cqeA02	28 Dec, 2014	1.10.510.10	Assigned
4cqeB01	28 Dec, 2014	3.30.200.20	Assigned
4cqeB02	28 Dec, 2014	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf