PDB 4cod

PDB Information

PDB4COD
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceMYCOBACTERIUM TUBERCULOSIS
Primary Citation
Encoded Library Technology as a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of Mycobacterium Tuberculosis Inha.
Encinas, L., O'Keefe, H., Neu, M., Remuinan, M.J., Patel, A.M., Guardia, A., Davie, C.P., Perez-Macias, N., Yang, H., Convery, M.A., Messer, J.A., Perez-Herran, E., Centrella, P.A., Alvarez-Gomez, D., Clark, M.A., Huss, S., O'Donovan, G.K., Ortega-Muro, F., Mcdowell, W., Castaneda, P., Arico-Muendel, C.C., Pajk, S., Rullas, J., Angulo-Barturen, I., Alvarez-Ruiz, E., Mendoza-Losana, A., Pages, L.B., Castro-Pichel, J., Evindar, G.
J.Med.Chem.
HeaderTransferase
Released2014-01-28
Resolution2.400
CATH Insert Date16 Feb, 2014

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
B 17 Feb, 2014 Chopped
D 17 Feb, 2014 Chopped
F 17 Feb, 2014 Chopped
H 17 Feb, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4codB00 07 Mar, 2014 3.40.50.720 Assigned
4codD00 07 Mar, 2014 3.40.50.720 Assigned
4codF00 07 Mar, 2014 3.40.50.720 Assigned
4codH00 07 Mar, 2014 3.40.50.720 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P9WGR1 INHA_MYCTU Mycobacterium tuberculosis H37Rv Enoyl-[acyl-carrier-protein] reductase [NADH]
P9WGR1 INHA_MYCTU Mycobacterium tuberculosis H37Rv Enoyl-[acyl-carrier-protein] reductase [NADH]
P9WGR1 INHA_MYCTU Mycobacterium tuberculosis H37Rv Enoyl-[acyl-carrier-protein] reductase [NADH]
P9WGR1 INHA_MYCTU Mycobacterium tuberculosis H37Rv Enoyl-[acyl-carrier-protein] reductase [NADH]