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PDB 4c7k

PDB Information

PDB4C7K
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Optimization of Brain Penetrant 11Beta-Hydroxysteroid Dehydrogenase Type I Inhibitors and in Vivo Testing in Diet- Induced Obese Mice.
Goldberg, F.W., Dossetter, A.G., Scott, J.S., Robb, G.R., Boyd, S., Groombridge, S.D., Kemmitt, P.D., Sjogren, T., Gutierrez, P.M., Deschoolmeester, J., Swales, J.G., Turnbull, A.V., Wild, M.J.
J.Med.Chem.
HeaderOxidoreductase
Released2013-09-23
Resolution1.910
CATH Insert Date09 Mar, 2014

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 10 Mar, 2014 Chopped
B 10 Mar, 2014 Chopped
C 10 Mar, 2014 Chopped
D 10 Mar, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4c7kA00 25 Apr, 2014 3.40.50.720 Assigned
4c7kB00 25 Apr, 2014 3.40.50.720 Assigned
4c7kC00 25 Apr, 2014 3.40.50.720 Assigned
4c7kD00 25 Apr, 2014 3.40.50.720 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
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