PDB 4c7j

PDB Links
Overview

PDB Information

PDB	4C7J
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Optimization of Brain Penetrant 11Beta-Hydroxysteroid Dehydrogenase Type I Inhibitors and in Vivo Testing in Diet- Induced Obese Mice. Goldberg, F.W., Dossetter, A.G., Scott, J.S., Robb, G.R., Boyd, S., Groombridge, S.D., Kemmitt, P.D., Sjogren, T., Gutierrez, P.M., Deschoolmeester, J., Swales, J.G., Turnbull, A.V., Wild, M.J. J.Med.Chem.
Header	Oxidoreductase
Released	2013-09-23
Resolution	2.160
CATH Insert Date	14 Sep, 2014

PDB Images (9)

Image of CATH 4c7j

4c7j

PDB 4c7j

Image of CATH 4c7jA

4c7jA

PDB Chain 4c7jA

Image of CATH 4c7jB

4c7jB

PDB Chain 4c7jB

Image of CATH 4c7jC

4c7jC

PDB Chain 4c7jC

Image of CATH 4c7jD

4c7jD

PDB Chain 4c7jD

Image of CATH 4c7jA00

4c7jA00

CATH Domain 4c7jA00

Image of CATH 4c7jB00

4c7jB00

CATH Domain 4c7jB00

Image of CATH 4c7jC00

4c7jC00

CATH Domain 4c7jC00

Image of CATH 4c7jD00

4c7jD00

CATH Domain 4c7jD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	15 Sep, 2014	Chopped
B	15 Sep, 2014	Chopped
C	15 Sep, 2014	Chopped
D	15 Sep, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4c7jA00	16 Sep, 2014	3.40.50.720	Assigned
4c7jB00	16 Sep, 2014	3.40.50.720	Assigned
4c7jC00	16 Sep, 2014	3.40.50.720	Assigned
4c7jD00	16 Sep, 2014	3.40.50.720	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1