PDB 4c4f

PDB Information

PDB4C4F
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Structure-Based Design of Orally Bioavailable 1H-Pyrrolo[3, 2-C]Pyridine Inhibitors of the Mitotic Kinase Monopolar Spindle 1 (Mps1).
Naud, S., Westwood, I.M., Faisal, A., Sheldrake, P.W., Bavetsias, V., Atrash, B., Cheung, K.J., Liu, M., Hayes, A., Schmitt, J., Wood, A., Choi, V., Boxall, K., Mak, G., Gurden, M., Valenti, M., De-Haven-Brandon, A., Henley, A., Baker, R., Mcandrew, C., Matijssen, B., Burke, R., Hoelder, S., Eccles, S.A., Raynaud, F.I., Linardopoulos, S., Van Montfort, R.L.M., Blagg, J.
J.Med.Chem.
HeaderTransferase
Released2013-09-05
Resolution2.360
CATH Insert Date08 Dec, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 09 Dec, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4c4fA01 10 Dec, 2013 3.30.200.20 Assigned
4c4fA02 10 Dec, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P33981 TTK_HUMAN Homo sapiens Dual specificity protein kinase TTK