PDB 4btu

PDB Information

PDB4BTU
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
5-Chlorothiophene-2-Carboxylic Acid [(S)-2-[2-Methyl-3-(2-Oxopyrrolidin-1-Yl)Benzenesulfonylamino]-3-(4-Methylpiperazin-1-Yl)-3-Oxopropyl]Amide (Sar107375), a Selective and Potent Orally Active Dual Thrombin and Factor Xa Inhibitor.
Meneyrol, J., Follmann, M., Lassalle, G., Wehner, V., Barre, G., Rousseaux, T., Altenburger, J., Petit, F., Bocskei, Z., Schreuder, H., Alet, N., Herault, J., Millet, L., Dol, F., Florian, P., Schaeffer, P., Sadoun, F., Klieber, S., Briot, C., Bono, F., Herbert, J.
J.Med.Chem.
HeaderHydrolase
Released2013-06-19
Resolution2.370
CATH Insert Date22 Dec, 2013

PDB Images (11)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 23 Dec, 2013 Chopped
B 23 Dec, 2013 Chopped
E 23 Dec, 2013 Chopped
F 23 Dec, 2013 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4btuA00 26 Dec, 2013 2.10.25.10 Assigned
4btuB01 26 Dec, 2013 2.40.10.10 Assigned
4btuB02 26 Dec, 2013 2.40.10.10 Assigned
4btuE00 26 Dec, 2013 2.10.25.10 Assigned
4btuF01 26 Dec, 2013 2.40.10.10 Assigned
4btuF02 26 Dec, 2013 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X