PDB 4btt

PDB Links
Overview

PDB Information

PDB	4BTT
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	5-Chlorothiophene-2-Carboxylic Acid [(S)-2-[2-Methyl-3-(2-Oxopyrrolidin-1-Yl)Benzenesulfonylamino]-3-(4-Methylpiperazin-1-Yl)-3-Oxopropyl]Amide (Sar107375), a Selective and Potent Orally Active Dual Thrombin and Factor Xa Inhibitor. Meneyrol, J., Follmann, M., Lassalle, G., Wehner, V., Barre, G., Rousseaux, T., Altenburger, J., Petit, F., Bocskei, Z., Schreuder, H., Alet, N., Herault, J., Millet, L., Dol, F., Florian, P., Schaeffer, P., Sadoun, F., Klieber, S., Briot, C., Bono, F., Herbert, J. J.Med.Chem.
Header	Hydrolase
Released	2013-06-19
Resolution	2.590
CATH Insert Date	22 Dec, 2013

PDB Images (11)

Image of CATH 4btt

4btt

PDB 4btt

Image of CATH 4bttA

4bttA

PDB Chain 4bttA

Image of CATH 4bttB

4bttB

PDB Chain 4bttB

Image of CATH 4bttE

4bttE

PDB Chain 4bttE

Image of CATH 4bttF

4bttF

PDB Chain 4bttF

Image of CATH 4bttA00

4bttA00

CATH Domain 4bttA00

Image of CATH 4bttB01

4bttB01

CATH Domain 4bttB01

Image of CATH 4bttB02

4bttB02

CATH Domain 4bttB02

Image of CATH 4bttE00

4bttE00

CATH Domain 4bttE00

Image of CATH 4bttF01

4bttF01

CATH Domain 4bttF01

Image of CATH 4bttF02

4bttF02

CATH Domain 4bttF02

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	23 Dec, 2013	Chopped
B	23 Dec, 2013	Chopped
E	23 Dec, 2013	Chopped
F	23 Dec, 2013	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4bttA00	26 Dec, 2013	2.10.25.10	Assigned
4bttB01	26 Dec, 2013	2.40.10.10	Assigned
4bttB02	26 Dec, 2013	2.40.10.10	Assigned
4bttE00	26 Dec, 2013	2.10.25.10	Assigned
4bttF01	26 Dec, 2013	2.40.10.10	Assigned
4bttF02	26 Dec, 2013	2.40.10.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P00742	FA10_HUMAN	Homo sapiens	Coagulation factor X
P00742	FA10_HUMAN	Homo sapiens	Coagulation factor X
P00742	FA10_HUMAN	Homo sapiens	Coagulation factor X
P00742	FA10_HUMAN	Homo sapiens	Coagulation factor X