PDB 4bti

PDB Information

PDB4BTI
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
5-Chlorothiophene-2-Carboxylic Acid [(S)-2-[2-Methyl-3-(2-Oxopyrrolidin-1-Yl)Benzenesulfonylamino]-3-(4-Methylpiperazin-1-Yl)-3-Oxopropyl]Amide (Sar107375), a Selective and Potent Orally Active Dual Thrombin and Factor Xa Inhibitor.
Meneyrol, J., Follmann, M., Lassalle, G., Wehner, V., Barre, G., Rousseaux, T., Altenburger, J., Petit, F., Bocskei, Z., Schreuder, H., Alet, N., Herault, J., Millet, L., Dol, F., Florian, P., Schaeffer, P., Sadoun, F., Klieber, S., Briot, C., Bono, F., Herbert, J.
J.Med.Chem.
HeaderHydrolase
Released2013-06-18
Resolution2.300
CATH Insert Date05 Jan, 2014

PDB Images (11)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 06 Jan, 2014 Chopped
B 06 Jan, 2014 Chopped
E 06 Jan, 2014 Chopped
F 06 Jan, 2014 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4btiA00 09 Jan, 2014 2.10.25.10 Assigned
4btiB01 09 Jan, 2014 2.40.10.10 Assigned
4btiB02 09 Jan, 2014 2.40.10.10 Assigned
4btiE00 09 Jan, 2014 2.10.25.10 Assigned
4btiF01 09 Jan, 2014 2.40.10.10 Assigned
4btiF02 09 Jan, 2014 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X